*There are no intoxicating effects from using CBD based products.
*The US HHS (Health and Human Services) holds a patent on the use of CBD for its medicinal benefits. US Patent 6630507 awarded in 2003 classifies cannabinoids as NEURON PROTECTANTS and ANTIOXIDANTS.
*Anti-tumor-Antioxidant-Anti-psychotic-Stress Reducing-Anti-inflammatory-neuron-Protectant - Help prevent Hearth Damage.
*CBD is an natural compound of the cannabis plant and can make up to 40 percent of the plant extract.
*Bussinesses infuse cannabidiol into food or drinks as another way of ingesting the medicine.
* most people claim when you ingest CBD, it works in the hour, but some claim it can take more than a month before any noticeable benefits. The amount of Cannabidiol in their product was not specified. Higher concentration of CBD will help to obtain faster results.
*Products with high does of Cannabidiol in them have faster medecinal benefits or effect.
*More benefits are derived from Cannabidiol when it is ingested vs smoked. However, smoking provides a faster delivery of the Cannabidiol molecule. If a person smokes it, Cannabidiol will exit the blood strem faster when smoked.
*FDA finally decides to allow trial runs of CBD even though there are already patents and existing medicines made from hemp. The FDA acts like they are unaware of the benefits. Maybe the FDA is acting like they do not know because they should be prosecuted for negligence if they did.
Due to its anti-inflammatory effect, cannabinoids may provide relief of joint pain and swelling, and decrease joint destruction and disease progression.
Administration of CBD protected joints against severe damage, decreased progression, and produced improvement of arthritis in animal models. Approximately 54 million adults and 300,000 children in the U.S. have been diagnosed with arthritis or some other type of rheumatic disease, according to the Arthritis Foundation (AF). If you consider all of the individuals who have arthritis but have not yet been diagnosed, the AF suggests that the true count is likely closer to 91.2 million in total. What’s worse is that the number is expected to grow by 49 percent by the year 2040. A few of the most problematic symptoms associated with arthritis include pain, stiffness, and movement issues within the joints, all of which can be severe with RA and worsen over time. Yet there are other symptoms that are just as troublesome, such as anxiety and depression. Not only that, but it can become especially trying when you have to contend with other health conditions that tend to coexist with arthritis, like heart disease, diabetes, and obesity. Some medications and treatment programs can potentially help ease these negative effects, but many people are searching for a more natural pain relief option. This is where CBD oil comes into play. One of the primary CBD oil benefits for rheumatoid arthritis sufferers is its positive effect on pain, and research confirms it. A study published in the journal Pain in December 2017 analyzed whether CBD could prevent osteoarthritis pain and joint neuropathy. Based on their findings, researchers affirmed that it did both, because it decreased joint inflammation and served as a protectant to the nerves.
Wondering if CBD for rheumatoid arthritis actually works?
Well wonder no more, because it most certainly does. Keep on reading to find out why.
As is the case with other diseases such as multiple sclerosis and psoriasis, rheumatoid arthritis (RA) is an autoimmune condition with no known antigen. In other words, it’s a disease wherein white blood cells – for apparently no rhyme or reason – attack healthy cells in the body’s major joint areas. This causes intense pain and inflammation in areas like the knees, ankles, fingers, and hips.
While most people are familiar with THC in the respect that it helps combat pain, Cannabidiol (CBD), in turn, has long since been proven as an effective treatment method for pain related to swelling and inflammation. And in fact, as we’ll discuss in this article, several studies have even been carried out specifically showcasing the drug’s potential therapeutic benefits on RA-related pain. If you’ve been waiting for a safe, all-natural, effective replacement for your prescription RA pain medications, CBD oil just might be the treatment option you’ve been waiting for. Like we mentioned, RA is an autoimmune disease that causes pain, severe inflammation, and loss of function in the joints.
In healthy individuals, proper joint functioning is administered in part by a layer of connective tissue called the synovium, which produces a lubricating mechanism called synovial fluid. In rheumatoid arthritis sufferers, the cells in the synovial tissue are attacked by the body’s immune system, causing them to thicken and subsequently damage surrounding cartilage and bone tissue. And while doctors are unsure of what exactly initiates the immune attack on the healthy cells, they have been able to determine several risk factors associated with developing rheumatoid arthritis: Sex: Women are more than three times likelier to develop RA than menGenetics: The presence of specific genes may cause increased susceptibility to environmental factors that trigger onset of the diseaseAge: People between the ages of 40 and 60 are most at risk for initial onsetObesity: Overweight individuals are more at risk for developing RA due to weaker metabolisms (which promote joint area inflammation).
Moreover, it is known that the presence of rheumatoid factor – a specific antibody in the bloodstream – is in some way responsible for initiating the white blood cell attack on healthy joint tissue, though its exact physiological mechanism(s) and/or environmental trigger(s) remain unknown. (Also, not all people who test positive for rheumatoid factor in the bloodstream end up displaying symptoms of RA). In terms of prevalence, the disease is estimated to affect about 1.5 million people, making it the second most common joint disease worldwide after osteoarthritis. Also, given the fact that RA is a systemic disease (meaning it affects other areas of the body), many sufferers will eventually experience subsequent complications with the skin, eyes, lungs, heart, kidneys, and nerve tissue. (RA) is an inflammatory type of arthritis that usually affects the knees and hands.Conventional (Non-CBD Related) Treatment Methods for RA. As it stands, the primary aim for current rheumatoid arthritis medications is to target localized inflammation. That is to say, to target the effects of the disease rather than the underlying cause of it. While unfortunate, this is thoroughly understandable; until the mechanism or genetic stimuli of rheumatoid factor is discovered (and thus the stimuli of the immune attack on joint tissue), the disease will have to remain existing as ‘treatable’ rather than ‘curable’. Naturally, the course and range of treatment options will be determined by the severity of RA expressed in any given individual.
For milder cases, standard over-the-counter NSAID’s (non-steroidal anti-inflammatory drugs) like ibuprofen, Aleve, Aspirin, and Bayer are recommended, and can be effective. However, rarely are these medications strong enough to alleviate conditions in the more advanced stages of the disease.
In more severe cases, many people will be prescribed pharmaceutical-strength drugs as a means to deal with the chronic pain. DMARD’s (disease-modifying anti-rheumatic drugs) and biologics are common options, but these treatments – in addition to being expensive – can be incredibly dangerous. They work to modify the immune system, with the goal being to minimize onset attacks on joint tissue, but in doing so they pose a severe risk of infection. Methotrexate, for example – one of the most commonly prescribed RA biologics – has been well-documented to increase risk of serious infections due to inhibited immune response.
Other popular RA DMARD’s (such as Minocin, Azulfidine, and Plaquenil) pose an equally dangerous risk. Opioid painkillers, the strongest pharmaceutical pain relievers on the market, are another common treatment option, but we hardly need to go into the myriad risks of abuse, reliance, and overdose potential that they present. And lastly, while surgery for rheumatoid arthritis is an option in some cases, it’s by no means a “guaranteed fix” as it often is with osteoarthritis (osteoarthritis is pain in the joints due to mechanical ‘wear and tear’ – not due to an autoimmune response). CBD for Rheumatoid Arthritis: Medical and Physiological Implications. What’s exciting about CBD oil as an emerging RA treatment is its proven physiological role as an immune modulator.
T-cells are a type of white blood cell that are crucial to the body’s ability to produce a healthy immune response. Likewise, they’ve also been shown to play a key role in the molecular onset of rheumatoid arthritis – they can be one of, if not the contributing factor to development of the disease.
In a recent study, however, CBD was proven to suppress localized T-cell function and activity, suggesting that the cannabinoid may be the only scientifically-backed drug capable of treating the underlying cause of RA. While this is no more than speculation at this point, the notion that the drug may play a key role in suppression of autoimmune responses is nothing short of phenomenal.
Of course, though, much more commonly understood and thoroughly studied has been CBD’s ability to suppress inflammation, and thereby minimize localized pain. This is where the drug has proven to be a viable treatment option for thousands upon thousands of RA sufferers, and is the reason why it’s allowed many to shed their pharmaceutical painkillers altogether.
Nausea and vomiting are linked to each other; you can not feel nauseous and have a vomit or expel the contents without being nauseated.
Both these feeling are different from each other. Nausea is defined as the feeling of discomfort related to the upper stomach in addition to an urge to expel contents or vomit.
Nausea is a debilitating condition where you have an urge to expel the contents of the stomach.
The phenomenon of nausea and vomiting involves the stimulation of the chemoreceptor zone which is responsible for identifying the emetic agents present in the blood. The chemoreceptor zone has two specific receptors,i.e., Dopamine D2 along with Serotonin 5-HT3 receptors. A study show that cbd relieved nausea and vomiting, the use of CBD oil for relieving the feeling linked with nausea and vomiting occurs by interaction with the 5HT3A receptors leading to reduced binding of serotonin with these receptors and eventually less nausea and vomiting.
Multiple causes are leading to vomiting and nausea such as anxiety, stress, pain, digestive issues, head injuries, arteries associated with the lower brain region or matters linked with the middle or inner ear.
The centers which regulate the phenomenon of nausea and vomiting are connected with the lower part of the brain.
Medications such as chemotherapy also play a leading role in the induction of vomiting or nausea due to the stimulation of regulatory centers located in brain or irritation of the digestive system. There are many medications available in the market which help in controlling the phenomenon of nausea and vomiting such as Bismuth Subsalicylate.
However, these drugs result in adverse effects which include constipation, darkened stools, ringing sounds and darker appearance of the tongue. Other than these side effects, there are rare acute effects as well which include a headache, confusion, depression, anxiety, stomach pain, breathing issues, diarrhea, dizziness, profuse sweating, thirstiness, and slurred speech along with the vision problems. To overcome these deleterious effects, the doctors and scientists have performed several studies to identify a natural compound which aids in controlling these two unusual phenomena,i.e., nausea and vomiting.
CBD oil has been revealed as a fantastic compound for reducing the effects of nausea and vomiting along with other numerous severe disorders. Given its infamous nature of producing insatiable cases of the “munchies,” it’s definitely no secret that marijuana is great at increasing appetite. In fact, you’re likely well aware that one of medical marijuana’s most common uses is to promote appetite in chronically ill patients suffering from the likes of cancer, aids, or related challenges like cachexia (wasting syndrome). However, these patients are typically treated with cannabis that is high in the psychoactive cannabinoid THC. In other words, “typical” marijuana that provides an associated cerebral high. To be clear, there have not to date been any definitive scientific or clinical studies carried out showing CBD to be an appetite stimulant on its own. Numerous studies have shown THC and whole-plant cannabis extracts, on the other hand, to function as efficient appetite stimulators. This article aims to review the potential for full-spectrum CBD to work in a similar manner, WITHOUT the high…]. You don’t need to be a lover of cannabis to know that it is world famous for providing “The Munchies.” While this state of extreme hunger has been so over-commercialized in media, there’s actually some truth behind it!
Okay – so we all know that THC is responsible for the high that weed is known best for! It is also well known that THC is the cannabinoid responsible for that sudden onset of insatiable hunger! But, given the fact that full-spectrum (whole plant extract) CBD has been shown to work in many of the same ways as other cannabinoids, is it also capable of increasing appetite? And if so, is it capable of doing so without providing any sort of mind-altering, psychoactive high? Indeed, the non-psychoactive element of marijuana that has taken America by storm in recent years may potentially have some of the same chemical and physiological characteristics that allow other active cannabinoids to work as an appetite-stimulant — which would make it perfect for patient’s who don’t want to get high!
What Causes Lack of Appetite?
We can experience a lack of appetite for dozens of reasons, and it is not always necessarily a serious problem. If you have a cold, a stomach upset, are pregnant, or even just ate a large meal the night before, you are more likely not to feel hungry (duh, right?). Lack of appetite is almost always short-lived, and more often than not it doesn’t require any specific medical attention. However, a lack of appetite in some cases can be a sign of something more serious, or even a side effect of some other underlying causes. While it may not seem to be a serious issue, a consistent lack of appetite can quickly develop into more severe problems such as anorexia, bulimia, or other eating disorders.
What Are the Traditional Treatments of Low Appetite?
For most sufferers of low appetite, it is not just a matter of “pushing past it” and eating. This is even truer when the lack of appetite is a result of a medical condition. However, like almost all prescription drugs, these often come with a long list of unpleasant side effects that usually do more harm than good. Moreover, we all know that many drugs and pharmaceutical prescriptions can be highly addictive.
When you notice a change in your diet pattern, the first step is to consult a doctor. Your doctor will prescribe treatments and therapies depending on your underlying condition. Pain relief may help ease the symptoms. If medication is the cause of your fatigue and loss of appetite, your doctor may adjust your dosage or swap the medication. Treating fatigue may include learning how to increase energy in your daily life. This can mean getting more exercise, creating a schedule for activity and rest, talk therapy etc.
Treating loss of appetite may include formulating a flexible meal schedule and incorporating favorite foods into meals. Studies also show that enhancing the taste and smell of foods can increase appetite in older adults.
Recent studies have found that those who consume cannabis in any form notice an increased appetite. However, the use of cannabis oil can help you regulate your appetite and encourage hunger. According to the National Cancer Institute, CBD oil stimulates appetite. Research shows that CBD bind to cannabinoid receptors in the body. Scientists believe that these receptors play an important role in regulating the feeding behavior of people. Therefore, CBD stimulates appetite whenever they settle on these receptors.
More research is been done for this treatment and CBD show a great potential play treament for appetite for this disorders.
A study, which included 4,657 adult men and women, showed that current marijuana use was associated with 16% lower fasting insulin levels, and smaller waist circumferences, a factor connected to the onset of diabetes.
Cannabidiol significantly reduced the development of diabetes in young non-obese mice, from 86% in non-treated mice to only 30% in mice treated with CBD. Cannabidiol can inhibit and delay the destruction of insulin-producing pancreatic cells and the production of inflammatory cytokines in diabetics. This data strengthens assumptions that CBD, which is known to be safe in humans, can possibly be used as a therapeutic agent for treatment of type 1 diabetes at an early stage of the disease. People prefer seeking alternative diabetes treatment options for a number of reasons. Beyond those looking for an all-natural alternative to the pharmaceutical industry, many concrete issues are related to diabetic medications. Insulin therapy, while beneficial for improving quality of life for Type II diabetes patients, often increases the risk for obesity and hyperglycemia. Considering diabetics have an increased risk of disease associated with weight gain, this can have huge ramifications for a patient's long-term health and wellness.
Research already has linked CBD to a higher metabolism rate, decreased fatty tissue, and increased breakdown of fat. Interestingly, despite the common assumption, one study into diabetic patients found that cannabis users also typically have a lower body mass index (ratio of weight to height) than non-users.
Another reason people with diabetes may wish to move away from insulin and other drugs is because of the often harsh side effects. One of the main issues with medications such as Sulfonylureas is an uncomfortable skin rash. Drugs such as Biguanides, Metformin, and Alpha-glucosidase inhibitors also can cause a variety of problems with the gastrointestinal system. Some side effects include gas, bloating, upset stomach, and diarrhea. Cannabidiol, in comparison, has no known risk of serious side effects. According to the available research on the topic, common side effects include dry mouth and a sense of calm. A gentle relaxation might not even be considered a side effect for some.
One issue that might come into play with CBD oil therapy is it affects how the liver metabolizes other pharmaceuticals. For those on a cocktail of medications, it is essential to consult with a medical professional to determine the proper dosage of CBD in combination with your other drugs. Because the liver takes longer to metabolize medicine when using CBD oil, other drugs actually may become more potent in the bloodstream. Many people find they need to reduce the dosage of other drugs during CBD oil therapy.For a deeper exploration into the low risk of CBD therapy.
One of the benefits of CBD is that patients can titrate the dose up or down quite easily. If the patient doesn't care for it, it can be discontinued without any withdrawal symptoms," Everything in the medical world is benefit vs. risk. Since CBD has been shown to be extremely safe, and because we know that the consequences of diabetes can be devastating, may be benefit from the addition of CBD to a regimen that includes healthy eating, exercise, and management of high glucose levels".
Studies show thay cbd reduced the hearth rate and blood presure in response to anxiety or stressful situations. The National Institutes of Health, published in 2010,
examined the possibility of CBD for treatment of cardiovascular complications.
In particular, they examined how CBD could potentially reduce the risk cardiomyopathy, which can develop even in well-managed diabetes. The review concluded that “Remarkably, CBD attenuated myocardial dysfunction, cardiac fibrosis, oxidative/nitrative stress, inflammation, cell death, and interrelated signaling pathway”.
Beyond the treatment of patients suffering from stroke and diabetes, CBD may also be able to provide daily protection from high blood pressure. Studies have shown that the endocannabinoid system is in large part responsible for the regulation of hypertension. This is a novel area of high blood pressure research. Cannabidiol has been known to regulate the activity of the endocannabinoid anandamide, which has been linked to the mediation of hypertension and other vasodilator activities.
What much of the current cardiovascular research has in common, is that it mainly explores the antioxidant and anti-inflammatory capabilities of CBD. These are perhaps two of the most thoroughly explored areas of CBD research. In many cases, even outside of heart health, CBD is well known for its ability to reduce oxidative stress and target inflammation. If CBD is known for nothing else, it is known for its anti-inflammatory capabilities.
For patients suffering from various forms of heart disease, inflammation is always a significant and ongoing concern. When the tissue surrounding the heart becomes inflamed due to a possible lack of blood and oxygen flow, the related tissue damage can be quite severe and even life-threatening. Vaping CBD keeps this inflammation in check by inhibiting the body’s ability to produce pro-inflammatory cytokines. In fact, some scientists even suspect that cannabinoids can actually reverse the heart-related tissue damage, although more medical research is still needed to confirm this theory While the majority of CBD research remains within the confines of the laboratory, the preliminary evidence overwhelmingly supports CBD as a safe treatment alternative. Especially do the prevalence of heart disease, it’s important for all possible therapeutic options to be on the table. The more we discover about CBD, the more potential it demonstrates in the fight against cardiovascular deterioration.
According to researchers, CBD has antidepressant-like effects in mice. Studies found that antidepressant effects of CBD were fast.
If you have a lack of interest in activities you used to love or been feeling sadness you can’t seem to shake, you could be suffering from depression.
Depression is an umbrella term for more specific types such as persistent depressive disorder, postpartum depression, bipolar disorder, psychotic depression, season affective disorder, and manic-depressive disorder. More than 325 million people of all ages suffer from depression across the globe, according to the World Health Organization. Depression is the leading cause of disability and is a significant contributor to the global burden of disease.
SYMPTOMS OF DEPRESSION
As mentions above, feelings of emptiness or sadness that stay longer than a few weeks may be a sign of depression. Other emotional symptoms include the following: Anxiety and restlessnessLoss of interest in favourite activitiesExtreme irritability over minor thingsFixation on things that have gone wrong or on the pastAnger management issuesThoughts of suicide or death.
Some physical symptoms include the following:
Unexplained aches and painsDebilitating fatigueDifficulty making decisions or concentratingIncreased or decreased appetiteInsomnia or sleeping too muchWeight loss or weight gain in children, depression may cause them to refuse to go to school and cling to their parents. Teens may being to avoid activities and friends and become excessively negative. Cannabis oil is a quicker alternative to antidepressants. It triggers the endocannabinoid system and accelerates the growth and development of nervous tissue with little to no side effects. Treating depression with cannabis oil is a natural remedy that provides patients peace of mind. It also helps to battle stress by relieving anxiety, combating insomnia, inducing hunger, providing energy and focus, and enhancing mood.
A 2006 study found that occasional or daily use of cannabis consumers have decreased levels of depressive symptoms than those who did not use cannabis. Another study found that the THC in cannabis oil can change an individual’s response to negative emotions or images by triggering the endocannabinoid system in the brain.
Because stress is one of the leading causes of depression, using cannabis moderately appears to stabilize moods and alleviate stress.
Depression can be a little more difficult to spot in older adults. Common signs may include withdrawal, sleep problems, or unexplained memory loss.
As with other complementary and alternative practices, some people with IBD use cannabis for other medications or treatment options haven’t relieved their
symptoms—particularly symptoms of pain, nausea, and lack of appetite—as well as to improve their overall mood. Some people with IBD turn to complementary and alternative
practices like medical marijuana because it gives them a sense of control over their disease, by giving them something that they can actively do to combat their symptoms.
Others feel that options like medical marijuana may have less side effects than other treatments. The combination of cbd and thc may reduce inflammation and relieve
symptoms of IBD, such as abdominant pain, diarhea and reduced appetite. However, there haven’t been enough research studies conducted on cannabis in people with IBD to
fully evaluate the safety and potential risks.
It is becoming well known that CBD and other cannabinoids are important in activating CB1 and CB2 cannabinoid receptors in the body’s endocannabinoid system. To test the effectiveness in controlling the inflammatory response in patients with confirmed Crohn’s disease, a placebo controlled clinical study involving twenty-one patients was conducted and the results published in July 2013 in the journal, Clinical Gastroenterology and Hepatology. These patients had a mean age of 40 and were not responding to traditional treatments. Of eleven patients who received the cannabis, not the placebo, ten of them experienced significant improvement in just eight weeks. Plus, there were no side effects of cannabis observed. This is a very encouraging study for those who want to try using CBD oil to manage, or even put into remission, their Crohn’s disease. If you are using full spectrum CBD oil with no THC, there are no psychotropic effects and you can use it while at work without getting drowsy or “high”.
The Crohn’s & Colitis Foundation of America (CCFA) has stated that several research studies have indicated that:
“As a potential therapy for inflammatory bowel disease (IBD), cannabis-based drugs may hold promise, according to a report published in the August issue of Gastroenterology”.
While the CCFA does not endorse smoking marijuana or hemp, they are calling for more research to be done into the use of cannabis to manage Crohn’s disease and other IBS conditions where gastrointestinal inflammation is the culprit of the distress.
This is significant because the CCFA was founded by traditional doctors and supported by the National Institutes of Health. This non-profit is also on the forefront of mainstream medical research. In the past centuries, different preparations of marijuana have been used for the treatment of gastrointestinal (GI) disorders, such as GI pain, gastroenteritis and diarrhea. Delta9-tetrahydrocannabinol (THC; the active component of marijuana), as well as endogenous and synthetic cannabinoids, exert their biological functions on the gastrointestinal tract by activating two types of cannabinoid receptors, cannabinoid type 1 receptor (CB1 receptor) and cannabinoid type 2 receptor (CB2 receptor). While CB1 receptors are located in the enteric nervous system and in sensory terminals of vagal and spinal neurons and regulate neurotransmitter release, CB2 receptors are mostly distributed in the immune system, with a role presently still difficult to establish. Under pathophysiological conditions, the endocannabinoid system conveys protection to the GI tract, eg from inflammation and abnormally high gastric and enteric secretion. For such protective activities, the endocannabinoid system may represent a new promising therapeutic target against different GI disorders, including frankly inflammatory bowel diseases (eg, Crohn's disease), functional bowel diseases (eg, irritable bowel syndrome), and secretion- and motility-related disorders. Researchers are conducting more study to find a way to treat this disease like many others, will cbd really be the answer to help many people on the world with this disease, time will tell.
The horrible irony is that the evolution of bacteria into “superbugs” is driven in large part by the antibiotics that were designed to treat them in the first place.
Methicillin-resistant Staphylococcus aureus (MRSA) for example, which causes over 10,000 deaths each year according to the Center for Disease Control (CDC), is a direct
byproduct of over-using antibiotics, which bred a stronger and more dangerous version of the common Staph aureus bacteria. MRSA, which infects open wounds and increases the
chance of death in patients by over 60 percent according to the CDC, is now wreaking havoc in hospitals and other facilities where it can spread easily between people in
close contact. Although MRSA is often associated with those with lowered immune systems, recently there have been outbreaks among healthy populations, including at a
New York State high school and other part of the country.
The situation has become so severe that in late 2014, President Obama issued an executive order devoted to combating antibiotic resistant bacteria, which he called “a serious threat to public health and the economy”. Obama even allotted $1.2 billion to the annual budget for the establishment of a special task force devoted to the issue, one that would develop an action plan for stopping the fast spread of antibiotic resistant bacteria like MRSA.
A Game Changing Study
In 2008, however, a first of its kind study conducted by a team of British and Italian researchers had already found that one of the world’s most commonly cultivated plants could stop MRSA in its tracks: marijuana. CBD showed some antimicrobial activity against methicillin resistant staphylococcus aereus(MRSA) a bacterium that causes difficult-to-treat infection. Specifically, the team tested five of marijuana’s most common cannabinoids against six different MRSA strains of “clinical relevance”, including epidemic EMRSA strains, which are the ones responsible for hospital outbreaks. They found that every single one of the cannabinoids tested showed “potent activity” against a wide variety of the bacteria.
Cannabinoids are substances unique to the cannabis plant that have wide-ranging medicinal properties: they fight cancer, reverse inflammation and act as powerful antioxidants. Now we know that they are also some of the most powerful antibiotics on earth. Amazingly, the cannabinoids even showed “exceptional activity” against a strain of the MRSA that had developed extra proteins for increased resistance to antibiotics, showing that cannabis remained effective despite the bacteria’s adaptations.
"The actual mechanism by which they kill the bugs is still a mystery…” said Gibbons. “I really cannot hazard a guess how they do it, but their high potency as antibiotics suggests there must be a very specific mechanism”. The researchers recommend cannabis as the source of new and effective antibiotic products that can be used in institutional settings right now. “The most practical application of cannabinoids would be as topical agents to treat ulcers and wounds in a hospital environment, decreasing the burden of antibiotics”. said Giovanni Appendino, a professor at Italy’s Piemonte Orientale University and co-author of the study. Since two of the most potently antibacterial cannabinoids were not psychoactive at all and appear in abundance in the common and fast-growing hemp plant, producing the antibiotics of the future could be quick and simple. “What this means is, we could use fiber hemp plants that have no use as recreational drugs to cheaply and easily produce potent antibiotics”. Appendino concluded.
How is that for an action plan, Obama?
The Hidden History Of A Miracle Plant
But introducing cannabis into the formal healthcare system is nothing new; the plant has been used as medicine by different cultures for millennia. A 1960 paper by Professors Dr. J. Kabelik and Dr. F. Santavy of Palacky University in the Czech Republic entitled Marijuana as a Medicament is perhaps the most comprehensive look at marijuana’s traditional use around the globe ever written. Surprisingly, the authors claim that for most cultures and for most time periods, cannabis was used as an antibiotic and treatment for chronic illnesses first and foremost, while its narcotic use is limited to certain areas and historical periods.
“All the information obtained from European folk medicine with regard to treatment with cannabis shows clearly that there do not appear to be any narcotic substances in it, or if there are then only in a negligible amount”, the authors claim. “Instead of that, emphasis has been laid on the antiseptic effect, hence on the antibiotic and to a small extent even on the analgetic (analgesic) effect”.
The same pattern was found in ancient Egypt, where “papyruses point fundamentally to antiseptic use” and in modern African tribes, where the “analgetic, sedative and antibiotic properties of cannabis in internal and external application are well known”. In South American folk medicine, marijuana was used for everything from gonorrhea to tuberculosis, according to the paper, and in Southern Rhodesia “it is a remedy for anthrax, sepsis, dysentery, malaria and for tropical quinine-malarial haemoglobinuria”. Even as late as the 19th century, cannabis was used by Western doctors to combat serious illnesses at home and abroad. An 1843 article in London’s Provincial Medical Journal, for example, chronicles an Irish doctor’s success in treating both tetanus and cholera in India by using cannabis in the form of crude hemp resin. Both these diseases are caused by bacteria and were major killers at the time.
A potent and commonly used medicine, cannabis was added to the official U.S. Pharmacopoeia in 1851, where it remained until it was removed in 1942. Coincidentally, the widespread manufacture and use of early commercial antibiotics — like penicillin, which was first isolated in 1929 but not mass produced until 1945 — happened at the same time as cannabis was taken out of medicinal use.
The next half a century saw the touting of antibiotics as miracle drugs while marijuana came to be almost completely associated with getting “high” — its potent medicinal properties obscured behind a cloud of fear and propaganda. It is only in the last couple of decades that the failure of antibiotics and clinical medicine to address a fast growing number of serious illnesses has driven people to rediscover the miraculous healing powers of this ancient plant. "Knowledge is Power".
Studies show cannabidiol inhibits prions, the proteins that cause fatal neurodegenerative diseases like Creutzfeldt-Jakob disease and mad cow disease, increasing the
survival time of infected mice by almost a week.
There’s actually only one piece of original research which investigates the ability of cannabis or cannabis-related compounds to counteract the effects of prion accumulation. In this study, published in 2007, researchers infected mice with scrapie (a prion disease originally found in sheep, and which is known to be related to BSE found in cattle) and then treated them with THC, CBD, anandamide, 2-AG, and two synthetic cannabinoids.
Here, we report that the nonpsychoactive cannabis constituent cannabidiol (CBD) inhibited PrPres accumulation in both mouse and sheep scrapie-infected cells, whereas other structurally related cannabinoid analogs were either weak inhibitors or noninhibitory.
Moreover, after intraperitoneal infection with murine scrapie, peripheral injection of CBD limited cerebral accumulation of PrPres and significantly increased the survival time of infected mice. Mechanistically, CBD did not appear to inhibit PrPres accumulation via direct interactions with PrP, destabilization of PrPres aggregates, or alteration of the expression level or subcellular localization of PrPsen. However, CBD did inhibit the neurotoxic effects of PrPres and affected PrPres-induced microglial cell migration in a concentration-dependent manner. The results suggest that CBD may protect neurons against the multiple molecular and cellular factors involved in the different steps of the neurodegenerative process, which takes place during prion infection. When combined with its ability to target the brain and its lack of toxic side effects, CBD may represent a promising new anti-prion drug. We will keep you posted!!!